Group members

José Luís Trejo Pérez
CSIC. Cajal Institute, Madrid.

Principal Investigator:
José Luís Trejo Pérez

Members of the equipment:
Sylvia Ortega Martínez.
Paloma Pérez-Domper.
Simona Gradari.

Publications group

• Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis.
  Llorens-Martín M, Tejeda GS, Trejo JL. PLoS One. 2010 Aug 16;5(8):e12188. PMID: 20808440
  
  
• Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.
  Llorens-Martín M, Torres-Alemán I, Trejo JL. Mol Cell Neurosci. 2010 Jun;44(2):109-17.
  PMID: 20206269 ofnsulin-like growth factor-I has complex effn structural plasticity in the hippocampus.
  
• Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus.
  Glasper ER, Llorens-Martin MV, Leuner B, Gould E, Trejo JL.
  Hippocampus. 2010 Jun;20(6):706-12. PMID: 19603528
  
  
• Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis.
  Llorens-Martín M, Torres-Alemán I, Trejo JL.
  Neuroscientist. 2009 Apr;15(2):134-48. PMID: 19307421
  
  
• The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis.
  Molecular & Cellular Neuroscience. 2008 Feb;37(2):402-11. Trejo JL, Llorens-Martín MV, Torres-Alemán I. Central act
  
  
• Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects.
  Molecular Psychiatry. 2007 Dec;12(12):1118-28. Trejo JL, Piriz J, Llorens-Martin MV, Fernandez AM, Bolós M, LeRoith D, Nuñez A, Torres-Aleman I. 
  
  
• Serum insulin-like growth factor I regulates brain amyloid-beta levels.
  Nature Medicine. 2002; 8(12):1390-7. Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I. 
   
• Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation.
  Development. 2001; 128(9):1481-92. Trejo JL, Pons S, Martínez-Morales JR, Martí E. 
  
  
• Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.
  Journal of Neuroscience. 2001; 21(5):1628-34. Trejo JL, Carro E, Torres-Aleman I.